How to get from Main St. & 2nd St. to Fort Myers, FL by bus?

Main St. & 2nd St. to Fort Myers, FL - Bus Schedule

The 27 bus from Main St. & 2nd St. to Fort Myers, FL runs from 6:26 AM to 6:37 PM, with departures every 1 hr 40 min-1 hr 50 min. The trip takes about 3 hr 25 min, with regular service throughout the operating hours.

From Main St. & 2nd St. to Fort Myers, FL by bus

To get from Main St. & 2nd St. to Fort Myers, FL you’ll need to take 3 bus lines: take the 27 bus from Main St. & 2nd St. station to Cypress Way E station. Next, you’ll have to switch to the 12 bus and finally take the FLIXBUS 2421 bus from Naples, FL station to Fort Myers Bus Stop station. The total trip duration for this route is approximately 3 hr 25 min. The bus schedule from Main St. & 2nd St. may change. We recommend you check the updated bus schedule to Fort Myers, FL on the Moovit app.

205min
Bus - 2727
Bus - 1212
Bus - FLIXBUS 2421FLIXBUS 2421
Walk to Fort Myers, FL
Leaves from Main St. & 2nd St.

Step by Step

  • 1
    Start from bus station
    Start from bus station
    Main St. & 2nd St.
  • 2
    Bus - 2727
    Wait for bus
    27
    Creekside Wlinc
  • 3
    Ride to bus station
    Ride to bus station
    Cypress Way E
    8 min
  • 4
    Walk to bus station
    Walk to bus station
    Cypress Way E
    140 yd • 2 min
  • 5
    Bus - 1212
    Wait for bus
    12
    Govt Center
  • 6
    Ride to bus station
    Ride to bus station
    Arbour Walk Cir
    12 min
  • 7
    Walk to bus station
    Walk to bus station
    Naples, FL
    ID TCN6
    430 yd • 6 min
  • 8
    Bus - FLIXBUS 2421FLIXBUS 2421
    Wait for bus
    FLIXBUS 2421
    Orlando (The Florida Mall)
  • 9
    Ride to bus station
    Ride to bus station
    Fort Myers Bus Stop
    ID FTM6
    45 min
  • 10
    Walk to Fort Myers, FL
    Walk to
    Fort Myers, FL
    60 yd • 1 min
*Duration based on 8am traffic
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Public transit directions from Main St. & 2nd St. to Fort Myers, FL

The distance between Main St. & 2nd St. and Fort Myers, FL is approximately 34.4 mi, which can typically be travelled in 205 min. Moovit will show you the directions from Main St. & 2nd St. to Fort Myers, FL by bus, so no matter how you choose to travel in Fort Myers – you will always have plenty of easy options.

Bus schedule from Main St. & 2nd St. to Fort Myers, FL

To check the bus schedule from Main St. & 2nd St. to Fort Myers, FL using the Moovit app, first download and open the app on your smartphone. Enter your starting point (Main St. & 2nd St.) and destination (Fort Myers, FL), then select the desired date and time of travel. Moovit will show all available bus routes, estimated travel times, and any required transfers. You can view detailed departure and arrival times for each bus, as well as real-time updates for delays or changes. Use this information to plan your trip and stay up to date with the latest bus schedules.

Related Routes

Questions & Answers

  • What is the fastest way to get from Main St. & 2nd St. to Fort Myers, FL?

    The fastest way takes 205 minutes, using Bus line 27, Bus line 12, Bus line FLIXBUS 2421.

  • Is there a direct bus between Main St. & 2nd St. and Fort Myers, FL?

    No, you’ll have to take 3 bus lines in total. The total travelling time is 3 hr 25 min.

  • Which bus line goes from Main St. & 2nd St. to Fort Myers, FL?

    The 27 bus line goes from Cypress Way E station near Main St. & 2nd St. in Lee County to Cypress Way E station. From there you’ll have to take one bus line till Cypress Way E station near Fort Myers, FL.

  • How long does it take to travel from Main St. & 2nd St. to Fort Myers, FL by bus?

    The total travel time between Main St. & 2nd St. and Fort Myers, FL by bus is about 3 hr 25 min.

  • Where do I get on the bus near Main St. & 2nd St. to get to Fort Myers, FL?

    Get on the 27 bus from the Cypress Way E stop near Main St. & 2nd St. in Lee County.

  • Where do I get off the bus when travelling between Main St. & 2nd St. and Fort Myers, FL?

    Get off the bus at the Cypress Way E stop, which is closest to Fort Myers, FL.

Popular Routes